نوع مقاله : مقاله پژوهشی
نویسندگان
1 استادیار رفتارحرکتی، دانشگاه بینالمللی امام خمینی (ره)
2 دانشیار فیزیولوژی ورزشی، دانشگاه بینالمللی امام خمینی (ره)
چکیده
هدف از این پژوهش تأثیریک دوره تمرینات هوازی بر میزان ﻋﺎﻣﻞ ﻧﻮروﺗﺮوﻓﻴﻚ ﻣﺸﺘﻖ از ﻣﻐﺰ (BDNF) و میزان توجه و تمرکز زنان سالمند بود. در این پژوهش نیمهتجربی، 19 زن سالمند با میانگین سن 2/4±3/58 بهطور تصادفی به دو گروه تجربی (10=n) و کنترل(9=n) تقسیم شدند. از همة آزمودنیها 24 ساعت قبل از شروع تمرین و 24 ساعت پس از پایان دورة آزمون، بهصورت ناشتا خونگرفته شد. دادهها با استفاده از آزمون توجه و تمرکز وینا (COG) جمعآوری شدند. مؤلفههای آزمون شامل تعداد انتخابهای صحیح، تعداد انصراف صحیح (شاخص سرعت پردازش در توجه)، میانگین زمان انتخاب صحیح (شاخص تمرکز) و میانگین زمان انصراف صحیح (توجه انتخابی) به آزمونها بود. گروه تجربی به مدت هشت هفته، هر هفته سه جلسه تمرین هوازی بهمدت 45-30 دقیقه با شدت 55-40 درصد ضربان قلب بیشینه تمرینات هوازی داشتند. گروه تمرینی در قیاس با گروه مرجع (نورم)، رتبة درصدی 87 را در پسآزمون احراز کرد. این در حالی بود که گروه کنترل رتبة درصدی 34 را احراز کرد. نتایج پژوهش نشان داد شاخصهای سرعت پردازش (P=0.001)، توجه انتخابی(P=0.001) و شاخص تمرکز (P=0.001) بهبود معنیداری یافت. ازآنجاکه ارتباط مستقیمی بین سطح BDNF و تمرینات هوازی وجود دارد و از طرفی تأثیر BDNF بر ویژگیهای شناختی روشن است، بنابراین تمرین هوازی با شدت متوسط میتواند زمینة بهبود ویژگیهای روانی حرکتی همچون توجه و تمرکز را مهیا کند.
کلیدواژهها
موضوعات
عنوان مقاله [English]
The Effect of Aerobic Exercise on Brain-derived Neurotrophic Factor and Attention of Elderly Females
نویسندگان [English]
- Morteza Taheri 1
- Khadijeh Irandoust 2
1 Assistant Professor of Motor Behavior, Imam Khomeini International University
2 Associate Professor of Exercise Physiology, Imam Khomeini International University
چکیده [English]
One of the main concerns of aged people is the attention attenuation in the aging period. Thus, the purpose of this study was to investigate the effect of aerobic exercise on Brain-derived Neurotrophic Factor (BDNF) and attention/ concentration of elderly females. It was a semi experimental study with 41 elderly subjects with mean age of 66±3.2yr whom were randomly assigned into either an exercise (EG, n=21) or a control group (CG, n=20). fasting blood test was taken 24 hours prior to experiment and 24 hours after the end of tests. COG test in Viena system was used to collect data.The aerobic training group trained for 8 weeks, 3 sessions per week, 30 to 45 hours in each session. The aerobic training performed with 40% to 55% of maximum heart rate. Training group had rank percentile of 87 compared to reference group while it was 34 for control group. The results suggested that speed processing(P=0.001)selective attention (P=0.001)and concentration (P=0.001) were significantly improved in the training group. Since a direct relationship has been foun between BDNF and Aerobic Excercises, besides, the positive eddefct of BDNF on cognitive capacities is well proven, therefore, a mild type of aerobic exercise colud imrove the psychomotor performance.
کلیدواژهها [English]
- Elderly
- BDNF
- Attention
- Concentration
2. Byun J-E, Kang E-B. The effects of senior brain health exercise program on basic physical fitness, cognitive function and BDNF of elderly women - a feasibility study. Journal of Exercise Nutrition & Biochemistry. 2016;20(2):8-18.
3. Kumar A., Foster TC. In: Brain Aging: Models, Methods and Mechanisms. Riddle DR., translator. CRC Press; 2007. pp. 229–41.
4. Sharifi G R, Bani Hashemi Emam Gheysi M, Rahnama N, Babai Mazrae No A R. Comparison of the Effect of 8 Weeks Aerobic Exercise With Resistance Exercise on Brain-Derived Neurotrophic Factor in Elderly Men. Salmand. 2015; 10 (3) :148-55.
5. Hofer M, Pagliusi SR, Hohn A, Leibrock J, Barde YA. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO J. 1990; 9(8): 2459-64.
6. Irandoost K, Taheri M, Seghatoleslami A. The Effects of Weight Loss by Physical Activity and Diet on Depression Levels of Highly Depressed Elderly Females. Salmand. 2015; 10 (1) :48-53.
7. Knaepen K, Goekint M, Heyman EM, Meeusen R. Neuroplasticity - exercise-induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects. Sports Medicine 2010; 40:765-801.
8. Zoladz JA, Pilc A, Majerczak J, Grandys M, Zapart-Bukowska J, Duda K. Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men. J Physiol Pharmacol. 2008; 59(Suppl 7): 119-32.
9. Byun J-E, Kang E-B. The effects of senior brain health exercise program on basic physical fitness, cognitive function and BDNF of elderly women - a feasibility study. Journal of Exercise Nutrition & Biochemistry. 2016;20(2):8-18.
10. Dishman RK., Berthoud HR., Booth FW., Cotman CW., Edgerton, Fleshner MR., Gandevia SC., Gomez-Pinilla F., Greenwood BN., Hillman CH., Kramer AF., Levin BE., Moran TH., Russo-Neustadt AA., Salamone JD., Van Hoomissen JD., Wade CE., York DA., Zigmond MJ. Neurobiology of exercise. Obesity. 2006;14:345–356.
11. Lee KJ., Rhyu IJ. Effects of exercise on structural and functional changes in the aging brain. J Korean Med Assoc. 2009;52:907–919.
12. Cognitrone-Handbuch. In: Schuhfried GmbH,editor. Modling: Dr. Schuhfried GmbH; 1994.
13. Kim BK., Rhim YT., Park IS. Effect of regular aerobic exercise on the prevention of cognitive decline and brain disease in elderly people. Journal of Korean Society for the Study of Physical Education. 2013;18:217229.
14. Park DC, Glass JM, Minear M, Crofford LJ. Cognitive function in fibromyalgia patients. Arthritis Rheum. 2001;44(9):2125–33.
15. Wang H, Ward N, Boswell M, Katz DM. Secretion of brainderived neurotrophic factor from brain microvascular endothelial cells. European Journal of Neuroscience. 2006; 23(6):1665-70.
16. Zoladz JA, Pilc A, Majerczak J, Grandys M, Zapart-Bukowska J, Duda K. Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men. J Physiol Pharmacol. 2008; 59(Suppl 7): 119-32.
17. Yarrow JF, White LJ, McCoy SC, Borst SE. Training augments resistance exercise induced elevation of circulating brain derived neurotrophic factor (BDNF). Neurosci Lett. 2010; 479(2): 161-5.
18. Chan KL, Tong KY, Yip SP. Relationship of serum brain-derived neurotrophic factor (BDNF) and health-related lifestyle in healthy human subjects. Neuroscience Letter. 2008; 447(2-3):124-28.
19. Neeper SA, Go mez-Pinnilla F, Choi J, Cotman CW. Physical activity increases mRNA for brainin-derived neurotrophic factor and nerve growth factor in rat brain. Brain Research. 1996; 726(12):49-56.
20. Currie JR, Ludlow H, Nevill A, Gilder M. Cardio-respiratory fitness, habitual physical activity and serum brain derived neurotrophic factor (BDNF) in men and women Neuroscience Letters. 2009; 451(1):152-5.
21. Uysal N, Kiray M, Sisman AR, Camsari UM, Gencoglu C, Baykara B, et al. Effects of voluntary and involuntary exercise on cognitive functions, and VEGF and BDNF levels in adolescent rats. Biotech Histochem. 2015; 90(1): 55-68.
22. Huang T, Larsen KT, Ried-Larsen M, Moller NC, Andersen LB. The effects of physical activity and exercise on brain-derived neurotrophic factor in healthy humans: A review. Scand J Med Sci Sports. 2014; 24(1): 1-10.